I've built a few 'race' motors and a few 'street' motors, and as above ,the difference will be minimal.... but there will be a difference ...
I've got a calculation around here somewhere that you put cam durations, valve diameters, piston diameter, rod length, stroke, etc etc into and the output was a perfect set of extractors for your motor...
Notice I say "Extractors" - most of us have "Headers" - very different...
Headers = more efficient exhaust than a cast-iron log
Extractors = Tuned-length, designed for a specific rev range.
Examples
On an escort 2.0 litre motor, very cammy (270' duration), pair of DHLA carbs, great ignition system ... Best design for the track was a 4-1 system with 41" primaries at 1.25" diameter .... collector was 3" and tapered down to a 2.5" main pipe with a mega-phone style exhaust (race engine - no mufflers back then

)
An 1100cc Mini Street engine (two inlet, three exhaust ports) - twin 1 1/4 SU carbs on BMC 'Log" inlet - we used a "LCB" design (Long centre branch) - the two outside pipes are shorter than the middle "shared" pipe by about 30% ! - very street friendly, and analogous to the 4/2/1 headers most of us run .... probably picked up around 5% under 4000 and maybe 7% above that ... - peak power happened around 6500, so not much point designing anything better
Torque under 4000 was down on the 'stock' motor, but from 6000-6800 the peak torque increased around 15% .. above this it dropped again ...
The secret is to match your components - your diff gearing, gearbox ratios, everything all the way though to the air-box works together ....
On the street and on a 'weekend warrior' its not worth the effort, but for a 'pure' race car its definitely worth the extra work ...
Wow, long answer, but it might help someone
J
PS - the Stroke to rod-length ratio is one of the most important parts of the calculations ..... Hmmm, might have to look into the Na6A engine one of these days .... looks like it might be a little powerhouse if treated right

If my calculations are correct, when this baby hits eighty-eight miles per hour ... you're gonna see some serious s**t.